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Babies with congenital heart disease are at greater risk of suffering brain injury and impaired brain growth. There is a significant gap in understanding the physiologic changes in cardiovascular and cerebral hemodynamics. The combination of serial cardiovascular and brain MRI has provided an opportunity to study the relationship between prenatal and postnatal physiology and brain development. It is likely that an improved understanding of the physiology that results in abnormal cerebral metabolism will lead to identifying the risk factors for abnormal brain development in congenital heart disease.
When: Wednesday, October 6, 2021
Time: 11:00 a.m. - noon p.m. EST
Learning objectives:
Review the epidemiology and phenotype of neurodevelopmental outcomes in congenital heart disease
Discuss the putative aetiologies of abnormal brain development in CHD
Consider the role of abnormal cardiovascular physiology in this pathogenesis and review how this might be mitigated
Mike Seed is the Division Head of Cardiology at SickKids in Toronto. He went to medical school at the University of Newcastle upon Tyne in the UK, where he also trained in paediatrics. He did residency training in Radiology at Leeds and a paediatric cardiology fellowship at SickKids. His clinical work at SickKids includes cross-sectional cardiac imaging and fetal cardiology. His research is in fetal and infant circulatory physiology and brain development. He is also working on a swine model of the artificial placenta.